Guan graduated in Zhonghua University, Western Painting, in Shanghai under the instruction of Chen Baoyi in 1927. In that same year, she went to Japan for advanced studies and enrolled in Cultural Institute of Tokyo, Japan. Her artworks have been exhibited by Nika Exhibition, Ueno Art Exhibition and Hyogo Art Exhibition on many occasions. In 1927, Japan's famous magazine published an article reporting Guan with high acclaim. In 1964, Guan's works were put on exhibition in Argentina. In 1972, her artwork Chrysanthemum was collected by Japan Cultural Exchange Association. In 1983, Guan's Violet was put on the collections' extibition-30th anniversary of the establishment of Shanghai Research Institute of Culture and History. Many of her works have been collected by galleries in Japan, Taiwan, Hong Kong, Macao, Canada, Britain and the USA. She passed away in Shanghai in 1986. She was the member of Shanghai Research Institute of Culture and History and China Artist Association.